Circ-POSTN promotes the progression and reduces radiosensitivity in esophageal cancer by regulating the miR-876-5p/FYN axis.

Alan ChuChen SunZongwen LiuShijia LiuMengxi LiRui SongLanlan GanYongtai WangRuitai Fan

Published in: Thoracic cancer (2024)

Circ-POSTN knockdown inhibited proliferation and invasion, but increased apoptosis and enhanced radiosensitivity in EC cells via modulating miR-876-5p/FYN axis, which might be a potential diagnostic and therapeutic target for EC.

Keyphrases

cell cycle arrest
induced apoptosis
cell death
endoplasmic reticulum stress
pi k akt
oxidative stress
signaling pathway
cell proliferation