Comparison of anticoagulation strategies for veno-venous ECMO support in acute respiratory failure.

Benjamin SeeligerMichael DöblerRobert FriedrichKlaus StahlChristian KühnJohann BauersachsFolkert SteinhagenStefan F EhrentrautJens-Christian ScheweChristian PutensenTobias WelteMarius M HoeperAndreas TiedeSascha DavidChristian Bode

Published in: Critical care (London, England) (2021)

In this retrospective study, ECMO management with high-dose heparinization was associated with lower rates of oxygenator changes and thromboembolic events when compared to a low-dose heparinization strategy. Prospective, randomized trials are needed to determine the optimal anticoagulation strategy in patients receiving ECMO support.

Keyphrases

respiratory failure
extracorporeal membrane oxygenation
high dose
low dose
atrial fibrillation
acute respiratory distress syndrome
venous thromboembolism
mechanical ventilation
stem cell transplantation
intensive care unit
hepatitis b virus