Determination of Region-Specific Roles of the M 3 Muscarinic Acetylcholine Receptor in Gastrointestinal Motility.

Yoko Igarashi-HisayoshiEikichi IharaXiaopeng BaiChika HigashiHiroko IkedaYoshimasa TanakaMayumi HiranoHaruei OginoTakatoshi ChinenYasushi TaguchiYoshihiro Ogawa

Published in: Digestive diseases and sciences (2022)

receptor has different region-specific roles in the motility function between the small intestine and colon in physiological and pathophysiological contexts. Selective PAMs designed for targeted subtypes of muscarinic receptors are useful for elucidating the subtype-specific function.

Keyphrases

biofilm formation
cancer therapy
escherichia coli
staphylococcus aureus
high resolution
drug delivery
mass spectrometry
simultaneous determination