Systemic Inflammatory Molecules Are Associated with Advanced Fibrosis in Patients from Brazil Infected with Hepatitis Delta Virus Genotype 3 (HDV-3).
Mauricio Souza CamposJuan Miguel Villalobos-SalcedoDeusilene Souza Vieira DallacquaCaio Lopes Borges AndradeRoberto José Meyer NascimentoSongeli Menezes FreireRaymundo ParanáMaria Isabel SchinoniPublished in: Microorganisms (2023)
Standard non-invasive fibrosis scores showed poor performance in HDV-3 infection. We here suggest that the determination of CCL19 and MCP.4 may be used to identify patients with advanced fibrosis. Moreover, this study gives novel insights into the immunopathogenesis of HDV-3 infection.