Cancer stem cell transcriptome landscape reveals biomarkers driving breast carcinoma heterogeneity.

Zhifa ZhangXiao ChenJianying ZhangKostya Ken Ostrikov

Published in: Breast cancer research and treatment (2021)

Our study contributes in identifying a CSC feature panel for breast carcinomas that drives breast carcinoma heterogeneity at the transcriptional level, which provides a reservoir for diagnostic marker and/or therapeutic target identification once experimentally validated as demonstrated by ATP6V1B1.

Keyphrases

single cell
cancer stem cells
rna seq
gene expression
machine learning
high grade
genome wide
oxidative stress
heat shock