Chitosan-Coated Azithromycin/Ciprofloxacin-Loaded Polycaprolactone Nanoparticles: A Characterization and Potency Study.

Alaa Eldeen YassinAbdulkareem M AlbekairyMustafa E OmerArwa AlmutairiYousef AlotaibiSalem AlthuwainiOsama Aql AlaqlShahad S AlmozaaiNouf Mohammed AlmutiriWed AlluhaimRaghad R AlzahraniAsma M AlterawiMajed A Halwani

Published in: Nanotechnology, science and applications (2023)

The co-encapsulation of AZ/CIP into chitosan-coated polymeric nanoparticles has been successfully achieved. The produced particles showed many beneficial attributes of uniform particle sizes below 200 nm and high zeta potential values. Chitosan-coated polymeric nanoparticles extensively enhanced the antibacterial activity of both AZ/CIP against bacteria.

Keyphrases

drug delivery
cancer therapy
wound healing
drug release
pseudomonas aeruginosa
hyaluronic acid
walled carbon nanotubes
multidrug resistant
photodynamic therapy