Sex differences in cerebral blood flow among adolescents with bipolar disorder.

Rachel H B MitchellAnahit GrigorianAndrew D Robertson Simina TomaNicholas J LuciwSudhir KarthikeyanHenk-Jan Mm MutsaertsLisa FiksenbaumArron W S MetcalfeBradley J MacIntoshBenjamin I Goldstein

Published in: Bipolar disorders (2023)

Greater CBF in female adolescents with BD versus HC in the precuneus/PCC may reflect the role of this region in the neurobiological sex differences of adolescent-onset BD. Larger studies targeting underlying mechanisms, such as mitochondrial dysfunction or oxidative stress, are warranted.

Keyphrases

cerebral blood flow
bipolar disorder
young adults
oxidative stress
major depressive disorder
physical activity
mental health
dna damage
cancer therapy
case control
childhood cancer
induced apoptosis
ischemia reperfusion injury
drug delivery
signaling pathway
endoplasmic reticulum stress