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Clinical outcomes of isolated deep grey matter infarcts after endovascular treatment of large vessel occlusion stroke.

Johanna OspelArnuv MayankWu QiuMohammed AlmekhlafiBijoy MenonRyan McTaggartRaul NogueiraAndrew DemchukManish JoshiCharlotte ZernaRene ChapotAditya BharathaAshutosh JadhavSimon NagelAlexandre PoppeMichael TymianskiMichael HillMayank Goyalnull null
Published in: Neuroradiology (2021)
Predominantly deep grey matter infarcts were seen in 316/1026 patients (30.8%). Compared to other patients, their ASPECTS was higher, collateral status and reperfusion quality were better and time to treatment was shorter. Good outcome was seen in 239/316 (75.6%) with vs. 374/704 (53.1%) without predominantly deep grey matter infarcts. After adjusting for baseline variables and total infarct volume, predominantly deep grey matter infarcts were independently associated with excellent outcome (adjOR: 1.45 [CI95: 1.04-2.02]), but not with good outcome (adjOR: 1.24 [CI95: 0.86-1.80]) or mortality (adjOR: 0.73 [CI95:0.39-1.35]) CONCLUSION: Predominantly deep grey matter infarct patterns were seen in 1/3rd of patients and were significantly associated with increased chances of excellent outcome, independent of patient baseline status and infarct size.
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