Validation of a Demography-Based Adaptive QTc Formula using Pediatric and Adult Datasets Acquired from Humans and Guinea Pigs.
Kazi T HaqKate McLeanGrace C Anderson-BarkerCharles I BerulMichael J ShattockNikki Gillum PosnackPublished in: bioRxiv : the preprint server for biology (2024)
) as population characteristics parametersˍUsing datasets from both pediatric and adult human subjects and an animal model, we demonstrate that the QTcAd formula is more effective at eliminating the QT-HR inverse relationship, as compared to other commonly used correction formulae.