Randomized, controlled clinical two-centre study using xenogeneic block grafts loaded with recombinant human bone morphogenetic protein-2 or autogenous bone blocks for lateral ridge augmentation.
Daniel Stefan ThomaMichael PayerNorbert JakseStefan P BienzJürg HüslerPatrick R SchmidlinUi-Won JungChristoph H F HämmerleRonald E JungPublished in: Journal of clinical periodontology (2017)
Both treatment modalities were successful in regenerating bone to place dental implants. PROMs did not reveal any significant differences between the groups except for pain during surgery at the recipient site (in favour of the test group). Histologically, a higher amount of mineralized tissue was observed for the control group at 4 months.
Keyphrases
- recombinant human
- minimally invasive
- bone regeneration
- soft tissue
- bone mineral density
- patient reported outcomes
- chronic pain
- double blind
- coronary artery bypass
- bone loss
- drug delivery
- open label
- genome wide
- placebo controlled
- cancer therapy
- single cell
- gene expression
- phase ii
- surgical site infection
- combination therapy
- spinal cord injury
- postoperative pain