Brain Responses to Propofol in Advance of Recovery From Coma and Disorders of Consciousness: A Preliminary Study.

The Adaptive Reconfiguration Index of patients who recovered from a disorder of consciousness at 3-month follow-up was linearly separable from that of patients who did not recover or remained in a chronic disorder of consciousness, on the single-subject level. EEG and propofol can be administered at the bedside with few contraindications, affording the Adaptive Reconfiguration Index tremendous translational potential as a prognostic measure of consciousness recovery in acute clinical settings.