Overall Efficacy and Safety of Safinamide in Parkinson's Disease: A Systematic Review and a Meta-analysis.

Riccardo GiossiFederica CarraraMartina MazzariFrancesco Lo ReMichele SenatoreAzzurra SchicchiFederica CorrùVeronica Andrea FittipaldoArianna PaniIrene TramacereAntonio Emanuele EliaFrancesco Scaglione

Published in: Clinical drug investigation (2021)

Overall, safinamide is effective in PDwMF patients taking L-dopa both at 100 and 50 mg daily. Evidence for efficacy in early PD is limited. Further trials are needed to better evaluate the anti-dyskinetic properties of safinamide.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
cerebral palsy
physical activity
peritoneal dialysis
patient reported