Integrative Analysis of Genome-Wide Association Studies and DNA Methylation Profile Identified Genetic Control Genes of DNA Methylation for Kashin-Beck Disease.

Ping LiCuiyan WuXiong GuoYan WenLi LiuXiao LiangYanan DuLu ZhangMei MaShiqiang ChengBolun ChengSen WangFeng Zhang

Published in: Cartilage (2019)

The results suggest that GC genes of DNA methylation may lead to the erosion of cartilage in KBD, which may help us in understanding the epigenetic alteration of KBD.

Keyphrases

dna methylation
genome wide
gene expression
genome wide association
copy number
bioinformatics analysis
extracellular matrix
mass spectrometry
transcription factor
network analysis
genome wide identification
solid phase extraction