Immunoreactivity to metal and silica associates with sarcoidosis in Dutch patients.

Els BeijerB MeekX BossuytS PetersR C H VermeulenH KromhoutM Veltkamp

Published in: Respiratory research (2020)

Immunoreactivity to silica and metals was only found in sarcoidosis patients, supporting the hypothesis that these antigens may be involved in the pathogenesis of a distinct subgroup of sarcoidosis patients. This indicates that when searching for causative agents in sarcoidosis patients, besides beryllium, also zirconium, aluminium and silica deserve clinical investigation.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
clinical trial
risk assessment
patient reported
heavy metals
health risk