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SPECT imaging of pulmonary vascular disease in bleomycin-induced lung fibrosis using a vascular endothelium tracer.

François HarelQuang T NguyenMohamed J NsaibiaVincent FinnertyArielle MorganMartin SiroisLouis VilleneuveAngelino CalderoneAlexandre BergeronEmmanuelle BrochieroJean-Claude TardifYanFen ShiJocelyn Dupuis
Published in: Respiratory research (2021)
SPECT imaging with 99mTc-PulmoBind detects PVD and its severity in bleomycin-induced lung fibrosis. Reduced AM receptor expression in human IPF supports further clinical development of this imaging approach.
Keyphrases
  • high resolution
  • high glucose
  • endothelial cells
  • nitric oxide
  • pet ct
  • idiopathic pulmonary fibrosis
  • drug induced
  • fluorescence imaging
  • computed tomography
  • mass spectrometry
  • photodynamic therapy
  • liver fibrosis