Guanmaitong Granule Attenuates Atherosclerosis by Inhibiting Inflammatory Immune Response in ApoE -/- Mice Fed High-Fat Diet.

Meng-Qi YangHuachen JiaoYan LiLei ZhangJuan Zhang Xia ZhongYitao Xue

Published in: Drug design, development and therapy (2022)

are the main ingredients of GMTG for treating AS. Further, GMTG could regulate the level of serum lipids and inhibit inflammatory immune response, which resulted in anti-AS effects such as plaque stabilization, reduction of plaque burden, and plaque remodeling. GMTG is a promising multi-target treatment for AS.

Keyphrases

high fat diet
immune response
insulin resistance
coronary artery disease
adipose tissue
oxidative stress
cardiovascular disease
high fat diet induced
signaling pathway
toll like receptor
metabolic syndrome
type diabetes
risk factors
wild type