Effect of glycosylation on the affinity of the MTB protein Ag85B for specific antibodies: towards the design of a dual-acting vaccine against tuberculosis.
Roberta BernardiniSara TengattiniZhihao LiLuciano PiubelliTeodora BavaroAnamaria Bianca ModoleaMaurizio MatteiPaola ContiStefano MariniYongmin ZhangLoredano PollegioniCaterina TemporiniMarco TerreniPublished in: Biology direct (2024)
Man to rAg85B-K30R/K282R could lead to the development of effective dual-acting vaccines against tuberculosis, stimulating protective antibodies against both AraMan and Ag85B, two key tuberculosis antigens.