Role of Gut Inflammation in Altering the Monocyte Compartment and Its Osteoclastogenic Potential in HLA-B27-Transgenic Rats.

Cecilia AnsaloneLotta UtriainenSimon MillingCarl S Goodyear

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2017)

Microbiota-dependent intestinal inflammation in B27-Tg rats directly drives the systemic inflammatory and bone-erosive potential of the monocyte compartment.

Keyphrases

oxidative stress
dendritic cells
endothelial cells
peripheral blood
bone mineral density
immune response
soft tissue