Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP.
Heena SainiMahima ChoudharyHarshita SharmaShibasish ChowdhurySudeshna MukherjeeRajdeep ChowdhuryPublished in: Molecular biology reports (2022)
Our study highlights the importance of GOF-P53 and YAP in NSCLC proliferation and proposes autophagy inhibition as an efficient strategy to attenuate NSCLC tumorigenesis.