Anticancer Potential of Novel Cinnamoyl Derivatives against U87MG and SHSY-5Y Cell Lines.

Niki GouleniAnnalisa Di RienzoSena OnerCeren KaragözMehmet Enes ArslanAdil MardinogluHasan Turkez Antonio Di Stefano Stamatia Vassiliou Ivana Cacciatore

Published in: Anti-cancer agents in medicinal chemistry (2023)

Cinnamoyl derivative 3e inhibits the proliferation of cultured U87MG and SHSY-5Y cells by inducing apoptosis. Further detailed research will be conducted to confirm these data in in vivo experimental animal models.

Keyphrases

cell cycle arrest
induced apoptosis
cell death
endoplasmic reticulum stress
pi k akt
signaling pathway
oxidative stress
endothelial cells
big data
cell proliferation
machine learning
human health
climate change
artificial intelligence
deep learning