Modulatory role of the orexin system in stress-induced analgesia: Involvement of the ventral tegmental area.
Kobra AskariShahrbanoo OryanAkram EidiJalal ZaringhalamAbbas HaghparastPublished in: European journal of pain (London, England) (2021)
Acute exposure to physical stress suppresses pain-related behaviors in the animal model of acute pain. Blockade of the OX1 and OX2 receptors in the VTA attenuates antinociceptive responses induced by FSS. The contribution of the OX2 receptors in the VTA is more predominant than OX1 receptors in stress-induced analgesia.
Keyphrases
- stress induced
- pain management
- liver failure
- chronic pain
- respiratory failure
- postoperative pain
- low density lipoprotein
- drug induced
- neuropathic pain
- aortic dissection
- spinal cord
- ultrasound guided
- mental health
- signaling pathway
- hepatitis b virus
- mechanical ventilation
- intensive care unit
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome