Phosphotungstic acid-enhanced microcomputed tomography for quantitative visualization of mouse mammary gland morphology.

Anthi KolokotroniEvi Gkikopoulou Vagelis Rinotas Eleni Douni

Published in: Journal of medical imaging (Bellingham, Wash.) (2023)

This work is the first study that employs PTA-enhanced microCT for 3D imaging and volumetric analysis of mouse mammary glands. Our results establish PTA-enhanced microCT as a useful tool for comparative studies of the mouse mammary gland morphology that can apply in mutant mice and for the preclinical evaluation of pharmaceuticals in breast cancer models.

Keyphrases

high resolution
type diabetes
cell therapy
mesenchymal stem cells
mass spectrometry
adipose tissue
young adults
fluorescence imaging
high fat diet induced
insulin resistance
electron microscopy
breast cancer risk