Allogeneic BK Virus-Specific T-Cell Treatment in 2 Patients With Progressive Multifocal Leukoencephalopathy.

Franziska HopfnerNora MöhnBritta Eiz-VesperBritta Maecker-KolhoffJens GottliebRainer BlasczykNima MahmoudiKaweh ParsOrtwin AdamsMartin StangelMike P WattjesGünter HöglingerThomas Skripuletz

Published in: Neurology(R) neuroimmunology & neuroinflammation (2021)

This study provides Class IV evidence that for patients with PML, allogeneic transplant of BKV-CTL improved symptoms, reduced MRI changes, and decreased viral load.

Keyphrases

stem cell transplantation
bone marrow
multiple sclerosis
hematopoietic stem cell
magnetic resonance imaging
high dose
contrast enhanced
computed tomography
sleep quality
diffusion weighted imaging
low dose
disease virus