Identification of Distinct Brain MRI Phenotypes and Their Association With Long-Term Dementia Risk in Community-Dwelling Older Adults.

Jasmin Annica Kuhn-KellerSigurdur SigurdssonBárbara Schmitz AbecassisIlse M J KantMark A Van BuchemLenore J LaunerMatthias J P van OschVilmundur G GudnasonJeroen de Bresser

Published in: Neurology (2024)

Distinct brain MRI phenotypes can be identified in community-dwelling older adults. Our results indicate that distinct brain MRI phenotypes are related to varying long-term risks of developing dementia. Brain MRI phenotypes may in the future assist in an improved understanding of the structural correlates of dementia predisposition.

Keyphrases

contrast enhanced
resting state
magnetic resonance imaging
white matter
mild cognitive impairment
diffusion weighted imaging
cognitive impairment
functional connectivity
cerebral ischemia
multiple sclerosis
magnetic resonance
risk assessment
brain injury
subarachnoid hemorrhage
climate change
human health