An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of lamotrigine in human serum and plasma.

Linda SalzmannTino SpeschaNeeraj SinghTobias SchierscherMartina BachmannFriederike BaulandAndrea GeistangerLorenz RischChristian GeletnekyChristoph SegerJudith Taibon

Published in: Clinical chemistry and laboratory medicine (2023)

This candidate RMP based on ID-LC-MS/MS provides a traceable and reliable platform for the standardization of routine assays and the evaluation of clinical samples.

Keyphrases

liquid chromatography tandem mass spectrometry
simultaneous determination
high throughput
ms ms
solid phase extraction
clinical practice
minimally invasive
tandem mass spectrometry
liquid chromatography
mass spectrometry
high resolution