Craniofacial anomalies in a murine model of heterozygous fibroblast growth factor 10 gene mutation.
Jenny TanMatthew L M JonesWarwick J TeagueSarbin RanjitkarPeter J AndersonPublished in: Orthodontics & craniofacial research (2023)
mutation was associated with craniomaxillary skeletal hypoplasia that probably arose from deficient (delayed) intramembranous ossification of the sutured bones. Overall, the skeletal and dental data suggest that the FGF10 gene plays an important role in the aetiology of craniofacial dysmorphology and malocclusion.