Melatonin inhibits NaIO 3 -induced ARPE-19 cell apoptosis via suppression of HIF-1α/BNIP3-LC3B/mitophagy signaling.
Kai WangYong-Syuan ChenHsiang-Wen ChienHui-Ling ChiouShun-Fa YangYi-Hsien HsiehPublished in: Cell & bioscience (2022)
-induced mitophagy of ARPE-19 cells via reduction in ROS-mediated HIF-1α targeted BNIP3/LC3B signaling in vitro and in vivo. Melatonin may be a potential therapeutic drug in the treatment of AMD.