Predictive and Prognostic Role of Tumor-Infiltrating Lymphocytes in Patients with Advanced Breast Cancer Treated with Primary Systemic Therapy.
Gaurav AgarwalK M M Vishvak ChantharShweta KatiyarNiraj KumariNarendra KrishnaniM SabaretnamGyan ChandAnjali MishraPunita LalPublished in: World journal of surgery (2023)
In this first study of its kind from a low- and middle-income country, high TILs concentration was found to be a predictor of response to PST across all breast cancer subtypes. TILs concentration was found predictive of better DFS and OS in TNBC and HER2-enriched cancers. Prognostic role of TILs in luminal cancers was not so apparent.