Identification of Symptoms Phenotypes of Hand Osteoarthritis using Hierarchical Clustering: Results from the DIGICOD Cohort.
Marie BinvignatGabriel PiresNicolas TchitchekFélicie CostantinoAlice CourtiesDavid KlatzmannAtul J ButteBernard CombeMaxime DougadosPascal RichetteEncarnita Mariotti-FerrandizFrancis BerenbaumJérémie SellamPublished in: Arthritis care & research (2022)
The identification of distinct clinical clusters based on HOA cardinal symptoms suggests previously undescribed subtypes of this condition warranting further study of biological characteristics of such clusters and opening a path toward phenotype-based personalized medicine in HOA.