Integrated epigenome, whole genome sequence and metabolome analyses identify novel multi-omics pathways in type 2 diabetes: a Middle Eastern study.

Noha A YousriOmar M E AlbaghaSteven C Hunt

Published in: BMC medicine (2023)

This study revealed several novel methylated genes in T2D, with their genomic variants and associated metabolic pathways with several implications for future clinical use of multi-omics associations in disease and for studying therapeutic targets.

Keyphrases

type diabetes
single cell
dna methylation
cardiovascular disease
gene expression
metabolic syndrome
glycemic control
skeletal muscle
amino acid