Obesity, risk of biochemical recurrence, and prostate-specific antigen doubling time after radical prostatectomy: results from the SEARCH database.
Stephen J FreedlandBrandee L BrancheLauren E HowardRobert J HamiltonWilliam J AronsonMartha K TerrisMatthew R CooperbergChristopher L AmlingChristopher J Kanenull nullPublished in: BJU international (2018)
While we confirmed that higher BMI was associated with BCR, we found no link between BMI and PSADT at the time of recurrence. Our data suggest obese men do not have more aggressive recurrences. Future studies are needed to test whether obesity predicts response to salvage therapies.
Keyphrases
- radical prostatectomy
- weight gain
- weight loss
- metabolic syndrome
- prostate cancer
- insulin resistance
- type diabetes
- body mass index
- high fat diet induced
- adipose tissue
- bariatric surgery
- free survival
- acute lymphoblastic leukemia
- electronic health record
- current status
- tyrosine kinase
- emergency department
- skeletal muscle
- machine learning
- physical activity
- deep learning