Clinical and economic impact of treated CMV infection in adult CMV-seropositive patients after allogeneic hematopoietic cell transplantation.
Regis Peffault de LatourPatrice ChevallierDidier BlaiseSarah AlamiLaurie Lévy-BachelotThierry AllavoineAbir TadmouriJosefin BlomkvistAlain DuhamelMicha SrourDavid BeauvaisIbrahim Yakoub-AghaPublished in: Journal of medical virology (2020)
In this large cohort of CMV-seropositive patients undergoing allo-HCT, treated CMV infection was significantly associated with an increased 1-year risk of overall mortality, with increased length of stay and with hospitalization cost. The burden of CMV disease in allo-HCT could be reduced in the future by appropriate prophylactic strategies.