A patient derived xenograft model of cervical cancer and cervical dysplasia.
Luke I LarmourFiona L CousinsJulie A TeagueJames A DeaneTom W JoblingCaroline E GargettPublished in: PloS one (2018)
The subrenal capsule can be used for a PDX model of human cervical cancer with a good engraftment rate and the ability to model in vivo characteristics of cervical cancer. For the first time we have demonstrated that cervical dysplasia and normal cervical tissue generated microscopic tissues in a PDX model.
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