Efficacy of ALK inhibitors on NSCLC brain metastases: A systematic review and pooled analysis of 21 studies.

Fausto PetrelliChiara LazzariRaffaele ArditoKaren BorgonovoAlessandra BulottaBarbara ContiMary CabidduJody Filippo CapitanioMatteo BrighentiMara GhilardiLuca GianniSandro BarniVanesa Gregorc

Published in: PloS one (2018)

Based on these data, ALK inhibitors are effective in both naive and pre-treated patients with similar IC ORR and IC DCR, irrespective of the line of therapy.

Keyphrases

brain metastases
small cell lung cancer
advanced non small cell lung cancer
electronic health record
hiv infected
big data
epidermal growth factor receptor
stem cells
machine learning
bone marrow
artificial intelligence