Intrahepatic bile duct primary cilia in biliary atresia.
Roberta FrassettoFilippo ParoliniSalvatore MarcedduGiulia SattaValeria PapacciuoliMaria Antonia PinnaAlessandra MelaGiannina SecchiGrazia GalleriRoberto ManettiLuisa BercichVincenzo VillanacciAntonio DessantiRoberto AntonucciFrancesco TandaDaniele AlbertiKathleen B SchwarzMaria Grazia ClementePublished in: Hepatology research : the official journal of the Japan Society of Hepatology (2018)
The presence of IHBC in BA livers at the diagnosis was associated with resolution of cholestasis, although was not predictive of short-term survival with native liver. Scanning electron microscopy represents a powerful new tool to study routine liver biopsies in biliary disorders. Cilia dysfunction in BA pathogenesis and/or disease progression warrants further investigation.