Transmembrane protein 108 inhibits the proliferation and myelination of oligodendrocyte lineage cells in the corpus callosum.

Yongqiang WuYanzi ZhongXufeng LiaoXiangguang MiaoJianbo YuXinsheng LaiYu ZhangChaolin MaHaili PanShunqi Wang

Published in: Molecular brain (2022)

Tmem108 inhibited OL progenitor cell proliferation and mitigated OL maturation in the corpus callosum, which may also provide a new role of Tmem108 involving bipolar disorder pathogenesis.

Keyphrases

bipolar disorder
signaling pathway
induced apoptosis
major depressive disorder
cell cycle arrest
endoplasmic reticulum stress
protein protein
oxidative stress
small molecule
cell proliferation