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Parkinson's Disease Tremor Differentially Responds to Levodopa and Subthalamic Stimulation.

Thomas WirthFrancisca FerreiraNirosen VijiaratnamChristine GirgesAshkan PakzadAlexis de RoquemaurelOlga SinaniJonathan HyamMarwan HarizLudvic ZrinzoHarith AkramPatricia LimousinThomas Foltynie
Published in: Movement disorders clinical practice (2023)
More severe postural tremor and less severe rest tremor were associated with both poorer levodopa and STN-DBS response. The different locations of clusters associated with best correction of tremor and other parkinsonian features suggest that STN-DBS effect on PD symptoms is underpinned by the modulation of different networks.
Keyphrases
  • deep brain stimulation
  • parkinson disease
  • drug induced
  • sleep quality