Targeting the SPHK1/S1P/S1PR2 axis ameliorates GH-secreted pituitary adenoma progression.

Heng SunBiao HuChunli WuTiejian Jiang

Published in: European journal of clinical investigation (2023)

Our study shows that blocking SPHK1/S1P/S1PR2 axis can ameliorate the progression of GHPA, providing evidence of a promising therapeutic target for GHPA.

Keyphrases

growth hormone
mouse model
cancer therapy
drug delivery