On the Alert for Cytokine Storm: Immunopathology in COVID-19.

Lauren A Henderson Scott W Canna Grant S SchulertStefano VolpiPui Y LeeKate F KernanRoberto CaricchioShawn MahmudMelissa M HazenOlha HalyabarKacie J HoytJoseph HanAlexei A GromMarco GattornoAngelo Ravelli Fabrizio De Benedetti Edward M Behrens Randy Q Cron Peter A Nigrovic

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2020)

Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID-19.

Keyphrases

coronavirus disease
sars cov
healthcare
respiratory syndrome coronavirus
type diabetes
adipose tissue
metabolic syndrome
social media
insulin resistance
drug induced