Systematic evaluation of SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.
Sophia HoberCecilia HellströmJennie OlofssonEni AnderssonSofia BergströmAugust Jernbom FalkShaghayegh BayatiSara MravinacovaRonald SjöberJamil YousefLovisa SkoglundSara KanjeAnna BerlingAnne-Sophie SvenssonGabriella JensenHenric EnstedtDelaram AfshariLan Lan XuMartin ZwahlenKalle von FeilitzenLeo HankeBen MurrellGerald McInerneyGunilla B Karlsson HedestamChristofer LendelRobert G RothIngmar SkoogElisabet SvenungssonTomas OlssonAnna Fogdell-HahnYlva LindrothMaria LundgrenKimia T MalekiNina LagerqvistJonas KlingströmRui Da Silva RodriguesSandra MuschiolGordana BogdanovicLaila Sara Arroyo MührCarina EklundCamilla LaghedenJoakim DillnerÅsa SivertssonSebastian HavervallCharlotte ThålinHanna TegelElisa PinAnna MånbergMy HedhammarPeter NilssonPublished in: Clinical & translational immunology (2021)
These observations demonstrate that a serological test based on a combination of several SARS-CoV-2 antigens enables a highly specific and sensitive multiplex serological COVID-19 assay.