Potential Cardiovascular and Metabolic Beneficial Effects of ω-3 PUFA in Male Obesity Secondary Hypogonadism Syndrome.
Annalisa NoceGiulia MarroneFrancesca Di DanieleManuela Di LauroAnna Pietroboni ZaitsevaGeorgia Wilson JonesAntonino De LorenzoNicola Di DanielePublished in: Nutrients (2020)
Long-chain ω-3 polyunsaturated fatty acids (PUFAs) are fundamental biocomponents of lipids and cell membranes. They are involved in the maintenance of cellular homeostasis and they are able to exert anti-inflammatory and cardioprotective actions. Thanks to their potential beneficial effects on the cardiovascular system, metabolic axis and body composition, we have examined their action in subjects affected by male obesity secondary hypogonadism (MOSH) syndrome. MOSH syndrome is characterized by the presence of obesity associated with the alteration of sexual and metabolic functions. Therefore, this review article aims to analyze scientific literature regarding the possible benefits of ω-3 PUFA administration in subjects affected by MOSH syndrome. We conclude that there are strong evidences supporting ω-3 PUFA administration and/or supplementation for the treatment and management of MOSH patients.
Keyphrases
- body composition
- insulin resistance
- metabolic syndrome
- weight loss
- case report
- weight gain
- high fat diet induced
- anti inflammatory
- end stage renal disease
- systematic review
- newly diagnosed
- ejection fraction
- chronic kidney disease
- resistance training
- stem cells
- mental health
- bone mineral density
- adipose tissue
- skeletal muscle
- risk assessment
- physical activity
- cell therapy
- patient reported outcomes
- mesenchymal stem cells
- climate change