Long-Acting Gel Formulations: Advancing Drug Delivery across Diverse Therapeutic Areas.
Hossein OmidianRenae L WilsonPublished in: Pharmaceuticals (Basel, Switzerland) (2024)
This multifaceted landscape of long-acting gels in diverse medical fields, aims to enhance therapeutic outcomes through localized treatment and controlled drug release. The objective involves advancements spanning cancer treatment, immunotherapy, diabetes management, neuroendocrine disorders, ophthalmic applications, contraception, HIV/AIDS treatment, chronic diseases, wound care, and antimicrobial treatments. It explores the potential of long-acting gels to offer sustained and extended drug release, targeted therapy, and innovative administration routes while addressing limitations such as scalability challenges and regulatory hurdles. Future directions focus on personalized therapies, biodegradability, combination therapies, interdisciplinary innovation, regulatory considerations, and patient-centric development. This comprehensive review highlights the pivotal role of long-acting gels in transforming therapeutic approaches and improving patient outcomes across various medical conditions.
Keyphrases
- drug release
- drug delivery
- hiv aids
- healthcare
- type diabetes
- cardiovascular disease
- cancer therapy
- antiretroviral therapy
- staphylococcus aureus
- case report
- combination therapy
- skeletal muscle
- single cell
- risk assessment
- climate change
- glycemic control
- pain management
- quality improvement
- insulin resistance
- wound healing
- health insurance
- replacement therapy
- affordable care act