Login / Signup

Predicting probability of tolerating discrete amounts of peanut protein in allergic children using epitope-specific IgE antibody profiling.

Maria SuprunPaul KearneyClive HaywardHeather ButlerRobert GettsScott Howard SichererPaul J TurnerDianne E CampbellHugh A Sampson
Published in: Allergy (2022)
Accurate predictions of food challenge thresholds are complex due to factors including limited responder sample sizes at each dose and variations in study-specific challenge protocols. Despite these limitations, an epitope-based predictor was able to accurately identify CTDs and may provide a useful surrogate for peanut challenges.
Keyphrases
  • young adults
  • single cell
  • high resolution
  • risk assessment
  • human health
  • climate change
  • mass spectrometry