Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest.
Josef DankiewiczTobias CronbergGisela LiljaJanus C JakobsenHelena LevinSusann UllénChristian RylanderMatt P WiseMauro OddoAlain CariouJan BělohlávekJan HovdenesManoj SaxenaHans KirkegaardPaul Jeffrey YoungPaolo PelosiChristian StormFabio S TacconeMichael JoannidisClifton CallawayGlenn M EastwoodMatt P G MorganPer NordbergDavid ErlingeAlistair D NicholMichelle S ChewJacob HollenbergMatthew ThomasJeremy BewleyKatie SweetAnders M GrejsSteffen ChristensenMatthias HaenggiAnja LevisAndreas LundinJoachim Pascal DüringSimon SchmidbauerThomas R KeebleGrigoris V KaramasisClaudia SchragEdith FaesslerOndrej SmidMichal OtáhalMarco MaggioriniWendel-Garcia Pedro DavidPaul JaubertJade M ColeMiroslav SolarOla BorgquistChristoph LeithnerSamia Abed-MaillardLeanlove NavarraMartin AnnbornJohan UndénIole BrunettiAkil AwadPeter McGuiganRoy Bjørkholt OlsenTiziano CassinaPhilippe VignonHalvor LangelandTheis LangeHans FribergNiklas Nielsennull nullPublished in: The New England journal of medicine (2021)
In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not lead to a lower incidence of death by 6 months than targeted normothermia. (Funded by the Swedish Research Council and others; TTM2 ClinicalTrials.gov number, NCT02908308.).