Pharmacokinetics of ceftriaxone, gentamicin, meropenem and vancomycin in liver cirrhosis: a systematic review.

M H ComceR A WeersinkU BeuersReinier M van HestM A Lantinga

Published in: The Journal of antimicrobial chemotherapy (2024)

Available data in studies of mostly moderate quality suggest that PK of ceftriaxone, meropenem and vancomycin are altered in cirrhosis. More advanced PK studies are needed to provide specific dosing recommendations.

Keyphrases

methicillin resistant staphylococcus aureus
case control
gram negative
electronic health record
high intensity
big data
clinical practice
quality improvement