Elevated levels of Interleukin-1β and IL-10 are associated with faster lung function decline in well-treated people with HIV.
Rebekka F ThudiumNicoline S ArentoftHedda HoelShoaib AfzalJakob H von StemannJulie Lyng FormanJon T WilckeThomas Lars BenfieldMarius TrøseidÁlvaro H BorgesSisse R OstrowskiJørgen VestboKen M KunisakiJens-Ulrik S JensenNicoline Stender ArentoftPublished in: The Journal of infectious diseases (2023)
Elevated IL-1β and IL-10 were independently associated with faster lung function decline in PWH, suggesting that dysregulated systemic inflammation may play a role in the pathogenesis of chronic lung diseases.