Impact of Hyperhomocysteinemia and Different Dietary Interventions on Cognitive Performance in a Knock-in Mouse Model for Alzheimer's Disease.
Hendrik NieraadNatasja de BruinOlga ArneMartine Catharina Josephine HofmannMike SchmidtTakashi SaitoTakaomi C SaidoRobert GurkeDominik SchmidtUwe TillMichael J ParnhamGerd GeisslingerPublished in: Nutrients (2020)
Despite prominent Aβ plaque deposition, the AppNL-G-F model merely displays a very mild AD-like phenotype at the investigated age. Older AppNL-G-F mice should be tested in order to further investigate potential effects of hyperhomocysteinemia and dietary interventions.