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A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model.

Ruta MaciulaitieneGiedrius KalesnykasDainius Haroldas PauzaIngrida Janulevičienė
Published in: PloS one (2024)
brimonidine eye drops supplemented with IP brimonidine injections improved RGC survival in a preclinical model of ONC.
Keyphrases
  • optic nerve
  • optical coherence tomography
  • stem cells
  • ultrasound guided
  • cell therapy
  • bone marrow
  • platelet rich plasma