Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists.

G KrivosheinE A TolnerAmjm van den MaagdenbergRashid Giniatullin

Published in: The journal of headache and pain (2022)

Together, we revealed a specific mechanosensitive profile of nociceptive firing in females and suggest TRPM3 channels as a potential novel candidate for the generation of migraine pain, with particular relevance to females.

Keyphrases

neuropathic pain
chronic pain
pain management
single cell
spinal cord injury
human health
postoperative pain