No impact of soluble epoxide hydrolase rs4149243, rs2234914 and rs751142 genetic variants on the development of type II diabetes and its hypertensive complication among Jordanian patients.

Maysoon KhameesYazun Bashir JarrarTariq Al-QirimIsmail Sami MahmoudMa'mon M HatmalWalhan AlshaerSu-Jun Lee

Published in: International journal of clinical practice (2021)

It can be concluded from this study that EPHX2 rs4149243, rs2234914 and rs751142 genetic variants do not play a role in the development of T2D and hypertension among Jordanian T2D patients. Further genetic studies with larger sample sizes are needed to find out the association of other functional EPHX2 variants with cardiovascular diseases among T2D patients in Jordan.

Keyphrases

end stage renal disease
ejection fraction
blood pressure
type diabetes
prognostic factors
gene expression
metabolic syndrome
adipose tissue
coronary artery disease
genome wide
copy number
insulin resistance
glycemic control